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For the past 33 years (PLUS for likely the next 8-16 years- because Biden is ALSO part of this group), all presidents save for two have been left-handed.
The two that were right-handed, Carter and Bush the Second, are pretty universally acknowledged as two of the worst presidents not only of the past half century but of our entire history. (and if you want to throw in another right-hander, Nixon, the list of worst presidents all being right-handed goes back to 1968, or forty years)
As a left-hander myself, I have a particular interest and some first hand (heh heh) familiarity with some of the potential psychology or physiology that may inform this set of occurrences.
I do have some theories as to why this might be, but I am interested in throwing the question out to others first.