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Going positive would be a great move on a lot of levels, including the most pragmatic of all: going negative hasn't helped her numbers a bit. (The exit polling in Wisconsin shows that voters thought she attacked Obama unfairly.)
She has to know that she has only the slimmest chance of winning now. If you slice and dice the latest Gallup numbers, it's clear that her support among key constituencies is eroding.
She has an opportunity to go out on a high note, with grace and warmth and dignity. She has a chance to send a message to her supporters that she's not a victim, and neither are they. She's a talented, accomplished woman who entered into a very tough competition and lost. Nothing was stolen from her, or them. She competed and she lost, and there's no shame in that.
That's an uplifting, inspirational message -- one of empowerment -- and her supporters need that right now.
After that, she can take a few months off to wallow in the blues, cuss out the campaign advisers who served her so poorly, and then get back to work keeping John McCain out of the White House.