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These ads aren't going after self-aware feminists, who likely aren't binge-drinkers. They're going after party girls, whose looks and need to have fun and meet guys in bars are everything to them. I've seen lots of women with masculine features, and plenty of transsexuals, and believe me, they don't look like that. (For one thing, they're more skillful at applying makeup.) Truly, that poor soul looks like Corporal Klinger from MASH after a bender and a bad bleach job.
In an ideal world, women would be more concerned with their health than their looks. But in this screwed-up society, that's not the case, and this is the kind of public service ad that really hits people hard. Intellectually I've always known about lung cancer, but the most compelling reason I never took up smoking is because I didn't want to ruin my singing voice. Whatever works, I say.