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The fears I have are more for the exploitation of animals. The mice bred to develop human breast cancer, for example, are probably not having the best lives, and are not expected to do so. A "mousy" mouse can lead a normal life, but a "mouse-human" mouse was not created for any use other than experimentation.
There are the non-genetic blends, too, such as the mice growing human ears on their backs. A biodegradable mold is place on the back, covered with human cartilage, and the mouse's skin and blood takes over supporting the ear. Eventually the biodegradable portion is completely replaced by mouse-grown human cartilage. In most cases the mouse survives the ear removal, but is the process ethically right?
There are cultures who regard other species as "peoples" of their own. If our culture were one such, I would have less concern over our mixing humans and animals. But we tend, in this country, to regard not only other species but our own as commodities. When we ourselves are not treating each other with respect, we should be even more cautious dealing with other species.
There are a couple of other reasons.
Reasons (not acceptable excuses, but at least understandable) to break the law about wiretapping:
Focussing solely on the "unbridled power" of the situation is to underestimate the machinations of the people involved in this. This behavior is not just a symptom of sheer desire for power, it has practical implications for consolidating and keeping that power. To fight this behavior effectively, you have to understand it fully. Know your enemy.
Note: I've written about this elsewhere, but it seemed worthwhile to mention here. My apologies if anyone already read some of this in my blog, though I find it unlikely ;-)